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糖尿病是全球性的流行病,是导致死亡和终末期肾病的主要原因,ACEI和ARB是两类RAS阻滞剂,公认的观点是两者较其他种类的降压药物具有更多的肾脏保护作用,且两者的肾保护作用相似。目前还没有在糖尿病患者中直接比较ACEI和ARB肾保护作用的研究,对采取何种药物的联合治疗的意见也不一致,本文旨在比较不同种类的降压药物,包括单药治疗、联合治疗伴有糖尿病的患者,对其生存率和主要肾脏结局的影响。
Diabetes is a global epidemic that is the leading cause of death and end-stage renal disease. ACEI and ARB are two types of RAS blockers, and the accepted view is that both have more renal protective effects than other classes of antihypertensive drugs , And both have similar renal protective effects. There is currently no direct comparison of the renal protective effect of ACEI and ARB in patients with diabetes and the inconsistent opinion on which combination of drugs to take. This article aims to compare the different types of antihypertensive drugs, including monotherapy, combination therapy Patients with diabetes have an impact on their survival and primary kidney outcomes.