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目的研究分析静脉预注甲氧明对剖宫产腰-硬联合麻醉低血压的防治效果。方法 80例行剖宫产产妇,随机分成对照组与观察组,每组40例。对照组采用剖宫产腰-硬联合麻醉时无预防措施;观察组在应用剖宫产腰-硬联合麻醉前给予静脉预注甲氧明。统计比较两组患者麻醉前(T1)、麻醉后5 min(T2)、麻醉后10 min(T3)以及手术结束(T4)时的血压、心率、新生儿血气指标水平以及不良反应情况。结果 T1时两组收缩压(SBP)、舒张压(DBP)及心率(HR)水平比较差异均无统计学意义(P>0.05);T2、T3、T4时观察组SBP、DBP与HR水平均显著高于对照组,差异均具有统计学意义(P<0.05)。观察组新生儿动脉血二氧化碳分压(Pa CO2)、动脉血氧分压(Pa O2)水平显著优于对照组,差异均具有统计学意义(P<0.05)。观察组麻醉术后低血压、恶心、心悸、心动过缓发生率2.50%、2.50%、0、2.50%均低于对照组15.00%、17.50%、10.00%、15.00%,差异均具有统计学意义(P<0.05)。结论静脉预注甲氧明在剖宫产腰-硬联合麻醉中能够有效预防低血压的发生,改善孕妇分娩结局,防治效果更佳,值得应用推广。
Objective To study the preventive and therapeutic effects of venous premetasthetic nailing on low-pressure anesthesia with lumbar-hard anesthesia in cesarean section. Methods 80 cases of cesarean section were randomly divided into control group and observation group, 40 cases in each group. Control group with cesarean section waist-hard anesthesia without prophylaxis; observation group before application of cesarean section waist-hard anesthesia intravenous premedication methoxyl. The blood pressure, heart rate, neonatal blood gas index and adverse reactions were compared between before anesthesia (T1), 5 min after anesthesia (T2), 10 min after anesthesia (T3) and the end of surgery (T4) Results There were no significant differences in SBP, DBP and HR between the two groups at T1 (P> 0.05). The levels of SBP, DBP and HR in the observation group at T2, T3 and T4 Significantly higher than the control group, the difference was statistically significant (P <0.05). The levels of PaCO 2 and Pa O 2 in the neonatal arteries of the observation group were significantly better than those of the control group (P <0.05). The incidences of hypotension, nausea, palpitations and bradycardia in the observation group were significantly lower than those in the control group (2.50%, 2.50%, 0,2.50%, 15.00%, 17.50%, 10.00%, 15.00% respectively) (P <0.05). Conclusions Intravenous pre-injection of methoxyl can effectively prevent hypotension during cesarean section combined with lumbar-hard anesthesia and improve the outcomes of delivery in pregnant women. The prevention and cure effect is better and should be applied and popularized.