据统计 ,2 0世纪 80、90年代以来各种药物或毒物致肾毒性、过敏性、肾内血流灌注下降已成为急性肾功能衰竭 (ＡＲＦ)的主要原因之一[1] 。引起ＡＲＦ的毒物种类多 ,病情发展迅速 ,尽管透析技术和护理水平有了很大提高 ,患者病死率仍超过 5 0 %。为探讨急性中毒致ＡＲＦ患者的临 According to the statistics, nephrotoxicity, allergy and decrease of intra-renal blood flow perfusion of various drugs or poisons have become one of the main causes of acute renal failure (ARF) since 1980s and 1990s [1]. ARF caused by many types of poison, the rapid development of the disease, despite the dialysis technology and care has greatly improved the level of patient mortality still exceeds 50%. To investigate the acute poisoning ARF patients