一步制粒是药粉的混合，制软材，成粒，干燥｝工序集于一个密闭容内，按某一确定好的程序依次完成的制粒过程。该项技术起源于德国，早年在化学工业上有所应用，本世纪60年代首次用于片剂的制粒，一经采用既获成功。我国在叨年代方才引进，现已得到制药企业的广泛认同，以下就 One-step granulation is the mixing of powders, making soft materials, granulation, and drying.} The process is set up in a closed volume and the granulation process is performed in sequence according to a defined procedure. This technology originated in Germany and was applied in the chemical industry in the early years. For the first time in the 1960s, it was used for the granulation of tablets. It was successfully used once it was adopted. China was introduced only in the late 1990s and has now been widely recognized by pharmaceutical companies.