应用 SDS- PAGE和 EL IB对十二指肠钩虫第三期幼虫和成虫可溶性抗原蛋白组份及免疫反应性进行了比较研究。SDS- PAGE电泳结果显示 ,钩虫幼虫和成虫蛋白区带数分别为 2 1条和 19条。EL IB反应表明 ,钩虫幼虫和成虫特异性抗原组份为 40～ 41k Da和 5 4～ 5 6 k Da。该结果为钩虫病免疫学及其疫苗的研究提供了科学资料 SDS-PAGE and EL-IB were used to compare the protein components and immunoreactivity of soluble antigen of larvae and adult larva of larva of hookworm. SDS-PAGE electrophoresis results showed that the number of larvae and adult protein zone of hookworm were 21 and 19, respectively. The EL IB reaction showed that the specific antigen components of larvae and adults of hookworm were 40 ~ 41kDa and 54 ~ 56kDa. The results provide scientific information for the study of hookworm immunology and its vaccine