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目的探讨儿童穿透性角膜移植术的手术技巧及对植片透明率的影响因素。方法采用穿透性角膜移植术对不同病因所致的儿童角膜混浊30例(33只眼)进行治疗,术后随访6个月至3年。结果植片透明率为66.7%,脱盲率为44.8%,其中先天性角膜混浊治疗的疗效较差,植片失败的主要原因为内皮型免疫排斥反应。结论儿童穿透性角膜移植术的效果较成人差,但从预防弱视和美容方面,积极争取早期手术是必要的。
Objective To investigate the surgical technique of penetrating keratoplasty in children and its influencing factors on the transparency of implants. Methods Penetrating keratoplasty was used to treat 30 cases (33 eyes) of children with different causes of corneal opacity. The patients were followed up for 6 months to 3 years. Results The transparence rate of grafts was 66.7% and the blinding rate was 44.8%. The curative effect of congenital corneal opacity was poor. The main reason of graft failure was endothelium-derived immune rejection. Conclusion Children penetrating keratoplasty has a poorer efficacy than adults, but it is necessary to strive for early surgery in the prevention of amblyopia and beauty.