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目的观察无创正压通气用于治疗重症支气管哮喘合并呼吸衰竭患者的临床效果。方法选取医院呼吸内科收治的重症支气管哮喘合并呼吸衰竭患者98例为研究对象,随机分为对照组和观察组,每组49例。对照组采用常规疗法治疗,观察组在对照组基础上采用无创正压通气辅助疗法治疗。观察2组动脉血气指标变化情况、临床疗效及并发症发生情况。结果治疗后,2组动脉血气指标均有所改善,且观察组改善程度优于对照组(P<0.05)。观察组治疗总有效率为91.8%,高于对照组的67.3%(P<0.05);观察组并发症发生率为4.1%,低于对照组的32.7%(P<0.05)。结论对于重症支气管哮喘合并呼吸衰竭患者而言,在常规治疗上结合无创正压通气可较快改善患者血气指标,明显提高临床疗效,对患者的抢救有重要意义,值得临床推广应用。
Objective To observe the clinical effect of noninvasive positive pressure ventilation in patients with severe bronchial asthma and respiratory failure. Methods A total of 98 patients with severe bronchial asthma and respiratory failure admitted to the hospital of respiratory medicine were selected as the research object and randomly divided into control group and observation group, with 49 cases in each group. The control group was treated by conventional therapy. The observation group was treated with noninvasive positive pressure ventilation on the basis of the control group. The changes of arterial blood gas index, clinical curative effect and complication of the two groups were observed. Results After treatment, arterial blood gas index in both groups improved, and the improvement in the observation group was better than that in the control group (P <0.05). The total effective rate of the observation group was 91.8%, higher than that of the control group (67.3%, P <0.05). The incidence of complications in the observation group was 4.1%, which was lower than that of the control group (32.7%, P <0.05). Conclusions For patients with severe bronchial asthma and respiratory failure, combining routine noninvasive positive pressure ventilation with conventional therapy can improve the blood gas index and improve the clinical curative effect significantly. It is of great significance to the rescue of patients and is worthy of clinical application.