Significant and various impacts of climate change have been observed in China, showing both positive and adverse effects, dominantly the latter, in different sectors and regions. It is very likely that future climate change would cause significant adverse impacts on the ecosystems, agriculture, water resources, and coastal zones in China. Adoption of adaptive measures to climate change can alleviate the adverse impact, therefore such measures should be incorporated into the medium-and long-term national economic and social development plans. Because China has done relatively limited research on impact assessment and our understanding of climate change is incomplete, the current impact assessment methodologies used and results obtained contain many uncertainties. To reduce the uncertainties and develop effective and practical climate change adaptive measures in China, it is necessary to emphasize regional case studies on adaptive measures, enlarge the scope of climate change research, and strengthen the assessment of the impacts resulted from extreme weather/climate events.