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我们在广西某肝癌高发区开展口服绿茶叶粉压片以预防原发性肝癌的实验流行病学研究。经过5年多的随访观察,结果表明:实验组成员死于肝癌的危险度明显低于对照组,效果指数(EI)为2.38,保护率(PR)为57%,差异有显著性意义(P<0.01).结果提示,对于已经长期暴露于肝癌危险因素的人群,采取某些非特异性的预防措施,仍然可以获得一定程度的保护。
We conducted an experimental epidemiological study on the prevention of primary hepatocellular carcinoma in a high incidence area of liver cancer in Guangxi. After more than 5 years of follow-up observation, the results showed that the risk of death from liver cancer in the experimental group was significantly lower than that of the control group. The effect index (EI) was 2.38, and the PR was 57%. The difference was significant. (P<0.01). The results suggest that for people who have been exposed to risk factors for liver cancer for a long time, certain non-specific preventive measures may still be able to obtain a certain degree of protection.