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对24例婴幼儿血管瘤患者(年龄1.5~19月),清晨顿服普萘洛尔1 mg/kg.d(年龄<6月)或1.5 mg/kg.d(年龄≥6月),动态调整剂量,疗程4~10月(平均7.4月)。总有效率100%,瘤体积消退50%以上的病例占77.7%。不良反应包括2例腹泻,好转继续服药;5例心率减慢,减慢幅度<20次/min;4例睡眠改变。安全性评定为19例安全,5例比较安全。随访5~12月,未见复发。
24 patients with infantile hemangiomas (age 1.5 to 19 months) were served morning with propranolol 1 mg / kg.d (age <6 months) or 1.5 mg / kg.d (age ≥ 6 months) Adjust the dose, treatment 4 to October (average 7.4 months). The total efficiency of 100%, tumor volume subsided more than 50% of the cases accounted for 77.7%. Adverse reactions included 2 cases of diarrhea, improvement continued to take medicine; 5 cases of heart rate slowed down, slowed down the rate of <20 beats / min; 4 cases of sleep changes. Safety was rated as 19 safe and 5 safe. Follow-up 5 to 12 months, no recurrence.