论文部分内容阅读
目的:探讨临床药师在妊娠晚期重度溃疡性结肠炎(UC)患者药物治疗中的作用。方法:临床药师参与1例妊娠晚期重度UC患者的治疗,协助医师从止泻、抗肠道炎症、调节肠道菌群、修复受损黏膜等角度对药物治疗方案进行了优化和完善,先后建议将蒙脱石散改为3 g,pr,qd,避免药物相互作用;换用氢化可的松100 mg,ivgtt,bid抗肠道炎症,待症状缓解后换用泼尼松30mg,po,qd+20 mg,po,qn;及时停用双歧杆菌三联活菌胶囊,补充人血白蛋白注射液、营养物质、氯化钾注射液、浓氯化钠注射液等。结果:医师采纳临床药师建议,患者病情好转,且所产男婴智力发育、体质量、身高变化与同月龄儿无显著差异。结论:临床药师协助医师优化和完善治疗方案,有助于临床合理用药,确保患者用药安全。
Objective: To investigate the role of clinical pharmacists in the treatment of patients with severe ulcerative colitis (UC) in the third trimester of pregnancy. Methods: The clinical pharmacist participated in the treatment of one severe third-trimester severe UC patient and assisted the physician in optimizing and perfecting the medication regimen from the aspects of anti-diarrhea, anti-intestinal inflammation, regulation of intestinal flora and repair of damaged mucosa. The montmorillonite powder was changed to 3 g, pr, qd, to avoid drug interactions; use hydrocortisone 100 mg, ivgtt, bid anti-intestinal inflammation, to be relieved after the switch to prednisone 30mg, po, qd +20 mg, po, qn; timely disable Bifidobacterium triple viable capsules, human albumin supplementation, nutrients, potassium chloride injection, concentrated sodium chloride injection. Results: The physician adopted the proposal of clinical pharmacists, the patient’s condition improved, and the baby boy’s intellectual development, body weight, height change had no significant difference with the same age. Conclusion: Clinical pharmacists assist physicians to optimize and improve the treatment plan, which helps clinical rational use of drugs and ensure the safety of patients.