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目的 探讨补碘对缺碘机体抗氧化能力的影响。方法 观察了缺碘地区人群口服碘油前后外周血超氧化物歧化酶（ＳＯＤ）水平的改变。结果 补碘之前，缺碘机体的血清ＳＯＤ水平高于正常对照组水平；补碘３～６个月之后其血清ＳＯＤ水平高于服药前的水平，３个月时其高于上限的比例显著增多，至１２个月时则显著减少。结论：补碘可导致缺碘机体ＳＯＤ水平升高，以增强机体的抗氧化能力。
Objective To investigate the effects of iodine supplementation on the antioxidative abilities in iodine deficient mice. Methods The level of superoxide dismutase (SOD) in peripheral blood of patients with iodine deficiency before and after oral administration of iodized oil was observed. Results Before iodine supplementation, the level of serum SOD in iodine deficient body was higher than that in normal control group. The level of SOD in serum after 3 ~ 6 months of iodine supplementation was higher than that before taking iodine, and the level of SOD was significantly higher than the upper limit at 3 months , Then significantly reduced by 12 months. Conclusion: Supplemental iodine can lead to the increase of SOD level in iodine deficient body to enhance the body’s antioxidant capacity.