自从Abelev(1963)、Tartarinov(1964)先后证明肝癌小鼠及病人血清中存在甲胎蛋白(aFP)以来,世界各国先后引进此项诊断技术。我国1971年后,在临床及肝癌普查工作中也采用了aFP 检测技术,先后在上海及重庆进行了4批肝癌普查,在约26万人中,检出较早期肝癌55人,充分说明了aFP 的诊断价值。通,过普查检出并随访了一批低aFP(<500ng/ml)肝癌患者、短期高aFP(>800 Since Abelev (1963) and Tartarinov (1964) have demonstrated the presence of alpha-fetoprotein (aFP) in the serum of hepatoma mice and their patients, the diagnostic techniques have been introduced successively by various countries in the world. After 1971, China also adopted aFP detection technology in the clinical and liver cancer census work. It has conducted four batches of liver cancer screening in Shanghai and Chongqing successively, detected 55 of the early stage liver cancer in about 260,000 people, and fully demonstrated that aFP The diagnostic value. Throughout the survey, a group of patients with low aFP (<500ng / ml) HCC were detected and followed up. Short-term high aFP (> 800