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近年来血管紧张素Ⅱ受体拮抗剂类药物在临床抗高血压治疗中的应用日益广泛。这类药物具有不良反应少、耐受性好及依从性高等优点。近年来很多研究发现其具有改善胰岛素敏感性与改善糖代谢作用,而不同ARB之间药代动力学与药效学各有不同。本文就其临床研究进展进行综述。
In recent years, angiotensin Ⅱ receptor antagonist drugs in the clinical antihypertensive treatment is widely used. Such drugs with less adverse reactions, tolerance and high compliance advantages. In recent years, many studies have found that it has the effect of improving insulin sensitivity and improving glucose metabolism, but different ARB pharmacokinetics and pharmacodynamics vary. This article reviews the progress of its clinical research.