目的研究分析重度子痫前期并发胎盘早剥的相关危险因素。方法 50例重度子痫前期并发胎盘早剥确诊患者作为观察组,50例未发生胎盘早剥的重度子痫前期患者作为对照组,比较两组产前血压、血清白蛋白、24 h尿蛋白水平及眼底小动脉出血、重度水肿发生率。结果观察组产前收缩压、舒张压水平均显著高于对照组,差异具有统计学意义(P<0.05)。观察组血清白蛋白、24 h尿蛋白水平均高于对照组,差异具有统计学意义(P<0.05)。观察组患者眼底小动脉出血以及重度水肿发生率分别为54.00%、70.00%,均明显高于对照组的14.00%、16.00%,差异具有统计学意义(P<0.05)。结论重度子痫前期并发胎盘早剥患者的相关危险因素主要有收缩压与舒张压、血清白蛋白、24 h尿蛋白水平过高及发生眼底小动脉出血以及重度水肿等,对于伴有上述因素的高危产妇,应提高并发胎盘早剥风险的预防。 Objective To analyze the related risk factors of placental abruption in severe preeclampsia. Methods Fifty patients with severe preeclampsia complicated with placental abruption were selected as the observation group and 50 patients with severe preeclampsia without placental abruption as control group. The levels of prenatal blood pressure, serum albumin, 24 h urinary protein And fundus arteriolar hemorrhage, severe edema incidence. Results The prenatal systolic blood pressure and diastolic blood pressure in the observation group were significantly higher than those in the control group, with statistical significance (P <0.05). The levels of serum albumin and 24 h urinary protein in the observation group were higher than those in the control group, with statistical significance (P <0.05). The incidence of fundus arteriolar hemorrhage and severe edema in observation group were 54.00% and 70.00%, respectively, which were significantly higher than those in control group (14.00% and 16.00%, respectively). The difference was statistically significant (P <0.05). Conclusion The main risk factors associated with placental abruption in patients with severe preeclampsia are systolic and diastolic blood pressure, serum albumin, 24-hour urinary protein levels and occurrence of fundus arteriolar hemorrhage and severe edema. For patients with severe preeclampsia complicated by placental abruption, High-risk maternal, should enhance the prevention of placental abruption risk.