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目的研究并探讨不同剂量的氟伐他汀对于高血脂症伴冠心病患者的临床治疗效果。方法以我院2008年12月～2011年12月期间共收治的100例高血脂症伴冠心病的患者为研究对象,并运用随机分组的方式将所有的患者分成两组,即治疗组和对照组分别由50例高血脂伴冠心病患者组成,对照组的患者运用氟伐他汀40g每天的剂量来进行治疗,而治疗组的患者则运用氟伐他汀80g每天的剂量来进行治疗,对比两组患者的临床治疗效果。结果两组患者在治疗之后血脂等各项指标均有明显的改善,且治疗组患者的临床治疗效果明显优于对照组患者,治疗者的50例高血脂伴冠心病患者中,显效的为32例,有效的为16例,治疗的总有效率为96%,对比P<0.05,具有显著的统计学意义。结论运用氟伐他汀的方式来治疗高血脂伴冠心病疾病具有非常显著的临床治疗效果,然而,大剂量的氟伐他汀与常规治疗的相比更能够降低患者的血脂水平,增强治疗效果。
Objective To study and investigate the clinical effects of different dosages of fluvastatin on patients with hyperlipidemia and coronary heart disease. Methods A total of 100 patients with hyperlipidemia and coronary heart disease were enrolled in our hospital from December 2008 to December 2011. All patients were divided into two groups randomly, ie treatment group and control group Group were composed of 50 cases of patients with hyperlipidemia and coronary heart disease, the control group of patients treated with fluvastatin 40g daily dose, while the treatment group of patients treated with fluvastatin 80g daily dose, compared with two groups The clinical effect of the patient. Results After treatment, the two groups of patients’ blood lipids and other indicators were significantly improved, and the clinical effect of the treatment group was significantly better than that of the control group. Among the 50 patients with hyperlipidemia and coronary heart disease, the effective rate was 32 Cases, effective for 16 cases, the total effective rate was 96%, P <0.05, with significant statistical significance. Conclusion The treatment of hyperlipidemia with coronary heart disease by fluvastatin has a very significant clinical therapeutic effect. However, fluvastatin at higher doses can lower the blood lipid level and enhance the therapeutic effect compared with conventional treatment.