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许多研究发现组织缺血损伤与细胞内钙超载有关。随着对钙通道特性及钙通道阻滞剂药理作用的深入研究,钙通道阻滞剂适用范围正从心脑血管疾病向其他领域扩展,它在眼科领域的研究正在深入。钙通道阻滞剂在视网膜缺血性损伤方面的保护作用目前正在研究,并已取得一些令人关注的结果,现将其保护作用综述如下。
Many studies have found that tissue ischemic damage and intracellular calcium overload. With the in-depth study on the characteristics of calcium channels and the pharmacological effects of calcium channel blockers, the application range of calcium channel blockers is expanding from cardiovascular and cerebrovascular diseases to other fields, and its research in ophthalmology is in-depth. The protective effect of calcium channel blockers on retinal ischemic injury is currently under study and some interesting results have been obtained. The protective effects of calcium channel blockers are summarized as follows.