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目的了解当前农村社区成人居民糖尿病发病与空腹血糖水平异常情况及其关系。方法采用流行病学队列研究设计,随访1908名参加基线调查的18~64周岁的农村社区居民。结果德清县农村社区居民糖尿病2年累积发病率为2.20%,使用2000年全国人口进行年龄和性别标化后的标化率为1.10%,在不同年龄组中发病率不同,且随着年龄明显上升;空腹血糖受损的2年累积发病率为4.67%(标化率为3.60%)。本次共随访3374.5人年,德清县农村社区18~64周岁成人糖尿病发病率为9.8/千人年。进一步分析表明,在调整了基线年龄、性别、文化程度、职业、BM I、吸烟、饮酒、规律体育锻炼和高血压之后,与基线空腹血糖<5.6mmol/L的队列成员相比,IFG明显增加了糖尿病发病风险;空腹血糖5.6~6.0mmol/L的人发生糖尿病风险增加了近7倍;基线空腹血糖每增加1 mmol/L,糖尿病发病风险增加近8倍。结论农村社区成人糖尿病和空腹血糖受损(IFG)发病处于较高水平,空腹血糖高,特别是IFG明显增加了糖尿病发病风险,而采用5.6mmol/L的诊断标准来判断是否空腹高血糖可能更有利于农村社区糖尿病防治,应加强对高空腹血糖人群的社区干预。
Objective To understand the prevalence of diabetes mellitus and fasting blood glucose in adults in rural communities and its relationship. METHODS: The epidemiological cohort study design was followed up with 1,908 rural community residents aged 18-64 who participated in the baseline survey. Results The cumulative incidence of diabetes in rural residents in Deqing county was 2.20% in two years. The standardization rate after the standardization of age and sex in 2000 was 1.10%. The incidence of diabetes in different age groups was different, Increased; the cumulative incidence of impaired fasting glucose 2 years was 4.67% (standardization rate was 3.60%). The total follow-up 3374.5 person-years, Deqing County, rural communities 18 to 64-year-old adult diabetes incidence was 9.8 / 1000 person-years. Further analysis showed that IFG was significantly increased compared to cohort participants with baseline fasting glucose <5.6 mmol / L after adjustment for baseline age, gender, educational attainment, occupation, BM I, smoking, drinking, regular physical activity and hypertension The risk of developing diabetes mellitus; the risk of developing diabetes in fasting blood glucose of 5.6-6.0mmol / L increased nearly 7-fold; for every 1 mmol / L of fasting blood glucose in baseline, the risk of diabetes increased nearly 8-fold. Conclusion The prevalence of diabetes and impaired fasting glucose (IFG) in rural adults is at a high level. Fasting plasma glucose, especially IFG, significantly increases the risk of diabetes. The diagnostic criteria of 5.6 mmol / L may be used to determine whether fasting hyperglycemia may be more Is conducive to the prevention and treatment of diabetes in rural communities, community interventions should be strengthened for people with high fasting blood glucose.