左氧氟沙星致Ⅲ度房室传导阻滞

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1例21岁女性患者因急性胃肠炎静脉滴注左氧氟沙星0.4 g,1次/d。第3次静脉滴注过程中,患者突然出现心慌、胸闷、头晕。急查心电图,示心率39次/min,Ⅲ度房室传导阻滞,交界性逸搏及室性逸搏。立即停用左氧氟沙星,26 min后Ⅲ度房室传导阻滞转为Ⅰ度房室传导阻滞,心率58~66次/min。“,”A 21-year-old female with acute gastroenteritis received an intravenous infusion of levofloxacin 0. 4 g,once daily. She developed palpitation,sense of suppression in the chest and dizzy suddenly during the intravenous infusion on day 3. Electrocardiographic examination showed the following results:heart rate 39 times/min,third degree atrioventricular block,junctional escape beat and ventricular escape. Levofloxacin was withdrawn immediately. Twenty-six minutes later,third degree atrioventricular block converted to first-degree atrioventricular block and the heart rate was 58-66 times/min spontaneously.
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