目的:比较不同补片固定方式在腹腔镜下疝修补术中的应用效果。方法:抽取2017年3月至2019年3月于鹤壁市人民医院或北京朝阳医院接受腹腔镜下疝修补术的100例腹壁切口疝患者，为全部患者及其家属讲解疝修补术不同补片固定情况，根据患者及家属选择补片固定方式分组，将其中48例选择钉合固定补片治疗的患者纳入对照组，52例选择医用生物胶固定补片治疗的患者纳入观察组。统计并比较两组临床指标；对比两组术后12、24、48、72 h时的疼痛程度[采用视觉模拟评分法(VAS)评估]；记录两组术后并发症的发生情况。结果:两组住院时间及拔除尿管时间比较，差异未见统计学意义(n P>0.05)；观察组住院费用少于对照组，差异有统计学意义(n P0.05); the hospitalization cost of the observation group was less than that of the control group, and the difference was statistically significant (n P<0.05); the VAS scores of bservation were lower than the that of control group, the difference was statistically significant (n P0.05).n Conclusions:Different patch fixation methods for laparoscopic hernia repair have different effects in the treatment of incisional hernia of the abdominal wall. Compared with the traditional nail fixation method, medical bio-gel fixation patches are more effective in reducing postoperative pain and have lower cost, higher safety, more conducive to patients’ recovery.