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目的探讨显微镜下经鼻蝶窦入路行垂体瘤切除术的临床疗效及对相关激素水平的影响。方法 100例垂体瘤患者,随机分为对照组(44例)和研究组(56例)。对照组行经口唇下-鼻中隔-蝶窦垂体瘤切除术,研究组行显微镜下经鼻蝶窦入路行垂体瘤切除术。对比分析两组治疗结果。结果治疗后,研究组手术时间、出血量明显优于对照组,差异有统计学意义(P<0.05);研究组泌乳素(PRL)和生长激素(GH)值均优于对照组,差异有统计学意义(P<0.05)。结论显微镜下经鼻蝶窦入路行垂体瘤切除术的临床疗效及对相关激素水平均有积极影响,具有实际应用价值。
Objective To investigate the clinical effect of pituitary adenoma resection through the nasospinal sinus under microscope and its effect on the level of related hormones. Methods 100 cases of pituitary tumor were randomly divided into control group (44 cases) and study group (56 cases). The control group underwent lip-nasal septum-sphenoidal sinus pituitary resection. The study group underwent microscopic pituitary adenoma resection through the nasospinal sinus. Comparative analysis of two groups of treatment results. Results After the treatment, the operation time and bleeding amount in the study group were significantly better than those in the control group (P <0.05). The values of PRL and GH in the study group were better than those in the control group Statistical significance (P <0.05). Conclusions The clinical effect of pituitary adenoma resection through the nasospinal sinus under the microscope and the related hormonal levels have a positive effect, which has practical value.