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目的分析2型糖尿病合并结直肠癌患者抗肿瘤治疗前后的营养状态,为更好地对患者进行营养管理提供参考。方法选取2013年6月至2014年12月在我院肿瘤中心住院治疗的2型糖尿病合并结直肠癌患者122例为研究对象,检测比较患者抗肿瘤治疗前、肿瘤治疗结束4周时的体质量、体质量指数、血红蛋白、前白蛋白水平;应用营养风险筛查工具NRS 2002对患者进行营养风险评估。结果与抗肿瘤治疗前比较,肿瘤治疗结束后4周时患者的前白蛋白、血红蛋白、体质量、体质量指数水平均显著下降(P<0.01),存在营养风险的患者的比例显著增加(P<0.01),患者NRS2002评分显著高于治疗前(P<0.01)。结论 2型糖尿病合并结直肠癌患者在抗肿瘤治疗后营养水平显著降低,营养风险发生率显著增加,该对该类患者应进行动态营养筛查和评估,及时为存在营养风险的患者制定个体化方案进行营养支持,以改善患者的营养状态,提高治疗效果。
Objective To analyze the nutritional status of patients with type 2 diabetes mellitus and colorectal cancer before and after anti-tumor therapy, so as to provide reference for better nutrition management of patients. Methods 122 patients with type 2 diabetes mellitus and colorectal cancer hospitalized in our hospital from June 2013 to December 2014 were enrolled in this study. Before and after the treatment of cancer, the body mass , Body mass index, hemoglobin, prealbumin level; nutritional risk assessment was performed on patients using NRS 2002, a nutritional risk screening tool. Results Compared with that before antitumor treatment, the levels of prealbumin, hemoglobin, body mass and body mass index decreased significantly (P <0.01) 4 weeks after the end of treatment and the proportion of patients at nutrition risk increased significantly (P <0.01). The score of NRS2002 in patients was significantly higher than that before treatment (P <0.01). Conclusions Patients with type 2 diabetes mellitus and colorectal cancer have significantly lower nutrition levels and a significantly higher nutritional risk after antitumor therapy. These patients should be screened and evaluated dynamically, and individualized patients should be timely provided with nutrition risk Nutritional support programs to improve the patient’s nutritional status and improve the treatment effect.