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目的:了解PCI术对冠心病患者血小板活性因子CD41、CD61的影响。方法:选择行PCI术的冠心病患者40例为病例组,行冠脉造影(CAG)术阴性的正常人20例为对照组。PCI组及对照组分别于术前、术后即刻、术后6h留取动脉血液标本测定CD41、CD61水平。结果:PCI组CD41、CD61水平术后6h>术后即刻>术前(P<0.05)。PCI组术前、术后即刻、术后6hCD41、CD61水平均高于对照组(P<0.05),差异有统计学意义。结论:PCI术作为一种机械性血管再通术,对冠心病患者的血小板活性有更强的影响。
Objective: To understand the effect of PCI on platelet activating factor (CD41) and CD61 in patients with coronary heart disease. Methods: Forty patients with coronary artery disease who underwent PCI were selected as the case group and 20 normal subjects who underwent coronary angiography (CAG) were selected as the control group. The levels of CD41 and CD61 in PCI group and control group were measured before operation, immediately after operation and 6 h after operation. Results: The levels of CD41 and CD61 in PCI group were significantly higher than those before PCI (P> 0.05). The levels of CD41 and CD61 in PCI group were significantly higher than those in control group immediately before operation, immediately after operation, and 6h after operation (P <0.05). The difference was statistically significant. Conclusions: PCI, as a mechanical revascularization, has a stronger effect on platelet activity in patients with coronary artery disease.