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目的:了解结节性脂膜炎的临床特点及疗效。方法:总结1997年~2008年经病理活检确诊的18例结节性脂膜炎患者的临床表现,分析其治疗方法及评价其疗效。结果:本病多发于中青年,女性居多,主要临床表现有皮下结节(100%)及发热(72%)。治疗上常规剂量糖皮质激素在皮肤型中的有效率达100%,系统型严重的需在糖皮质激素基础上加用免疫抑制剂。结论:常规剂量糖皮质激素对大部分患者疗效良好,尤其适用于皮肤型患者。
Objective: To understand the clinical features and efficacy of nodular panniculitis. Methods: The clinical manifestations of 18 patients with nodular panniculitis confirmed by pathological biopsy from 1997 to 2008 were summarized. The treatment and evaluation of the curative effect were analyzed. Results: The disease occurred in middle-aged and young women, the majority of women, the main clinical manifestations of subcutaneous nodules (100%) and fever (72%). Treatment of conventional dose glucocorticoid skin type in the effective rate of 100%, severe systemic need to add glucocorticoid based on the use of immunosuppressive agents. CONCLUSION: Conventional doses of glucocorticoids are effective in most patients and are particularly suitable for skin-typed patients.