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目的:观察序贯疗法和标准三联疗法对根除幽门螺杆菌(HP)的疗效。方法:将符合条件的200例患者随机分成观察组和对照组,每组100例。观察组予序贯疗法,对照组予标准三联疗法。停药1个月后复查14C尿素呼气试验,比较两组HP根除率以及不良反应情况。结果:根除率观察组为88.7%,对照组为75.8%,差异有统计学意义(P<0.05)。结论:序贯疗法根除HP效果优于标准三联疗法,且不良反应少,值得推广。
Objective: To observe the effect of sequential therapy and standard triple therapy on eradication of Helicobacter pylori (HP). Methods: 200 eligible patients were randomly divided into observation group and control group, 100 cases in each group. The observation group was given sequential therapy, while the control group was given standard triple therapy. One month after discontinuation of 14C urea breath test review, comparison of two groups of HP eradication rate and adverse reactions. Results: The eradication rate was 88.7% in the observation group and 75.8% in the control group, the difference was statistically significant (P <0.05). Conclusions: Sequential therapy is superior to standard triple therapy in eradicating HP and has fewer side effects and is worth promoting.