奥沙利铂为第三代铂类药物,临床应用广泛。近年来国内有文献报道,本品致咽喉痉挛,现摘要如下。安煜致[1]报道,男,49岁,因胃癌术后肝转移给予奥沙利铂150 mg治疗,用药后0.5 h出现呼吸困难并逐渐加重,10 min后出现口周肌肉痉挛、不能平卧、大汗淋漓,即予对症处理,15min后上述症状 Oxaliplatin is the third generation of platinum drugs, widely used in clinical practice. In recent years, there are domestic literature reports, this product caused by throat spasms, are summarized as follows. An Yuzhi [1] reported that male, 49 years old, was given 150 mg of oxaliplatin due to postoperative liver metastasis of gastric cancer. After 0.5 h of medication, he developed dyspnea and gradually increased. After 10 min, he had peripheral muscle spasm and could not flatten Lying, sweating, that is symptomatic treatment, 15min after the above symptoms