论文部分内容阅读
目的探讨连续性肾脏替代治疗(CRRT)不同治疗模式在肝素抗凝条件下,连续静脉-静脉血液透析(CVVHD)与连续静脉-静脉血液滤过(CVVH)对血小板的影响。方法于信宜市人民医院2010年10月至2014年10月行CRRT治疗患者中抽样选取68例均分为两组,在普通肝素常规抗凝条件下,34例给予CVVH模式治疗(对照组),另外34例给予CVVHD模式治疗(试验组),比较其对血小板的影响。结果治疗后,试验组血小板由(205.47±69.50)×109/L降至(173.73±57.53)×109/L,而对照组血小板则由(197.11±70.07)×109/L降至(82.61±15.44)×109/L,二者相比,对照组血小板下降趋势较试验组更显著,差异有统计学意义(P<0.01)。结论肝素抗凝条件下,CVVH治疗模式对血小板的影响较CVVHD大。
Objective To investigate the effects of continuous veno-venous hemodialysis (CVVHD) and continuous veno-venous hemofiltration (CVVH) on platelets in different treatment modalities of continuous renal replacement therapy (CRRT) under heparin anticoagulation. Methods Sixty-eight patients in CRRT-treated patients from October 2010 to October 2014 in Xinyi Municipal People’s Hospital were divided into two groups. Under routine heparin anticoagulation, 34 patients were given CVVH mode treatment (control group) , Another 34 cases were given CVVHD mode treatment (experimental group), compared to its impact on platelets. Results After treatment, the platelet count in the experimental group decreased from (205.47 ± 69.50) × 109 / L to (173.73 ± 57.53) × 109 / L, while that in the control group decreased from (197.11 ± 70.07) × 109 / L to (82.61 ± 15.44 ) × 109 / L, both compared to the control group, the trend of platelet decline more significantly than the experimental group, the difference was statistically significant (P <0.01). Conclusions Under heparin anticoagulation, the effect of CVVH treatment on platelets is greater than that of CVVHD.