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目的 了解近 10年来克山病病情发展趋势 ,为控制病情提供依据。方法 按照《全国克山病监测方案》要求进行。结果 10年监测期间全县未见急 (亚急 )型发病 ;监测点年新发生率 8.0 /万 ,全县农业人群慢型克山病平均患病率为 4.95 /万 ,年平均新发现率 0 .71/万 ,死亡率 0 .44 /万 ,5年累积死亡率降至 15 .2 %,10年累积死亡率仍达 75 .3 %。结论 膳食质量提高和人体硒水平提高可能是近 10年以来克山病病情相对稳定的主要原因 ;慢型克山病早期诊断及治疗方法研究应视为当前克山病临床研究重点 ;CVB在本病发生发展中的作用值得进一步探讨
Objective To understand the development trend of Keshan disease in the past 10 years and provide basis for controlling the disease. Methods According to the “national Keshan disease monitoring program” requirements. Results No acute (subacute) disease occurred in the county during the 10-year monitoring period. The annual incidence rate of monitoring sites was 8.0 / million. The average prevalence rate of chronic Keshan disease among agricultural population in the county was 4.95 / The mortality rate was 0.44 / million, the cumulative 5-year mortality rate dropped to 15.2%, and the cumulative 10-year mortality rate still reached 75.3%. Conclusion The improvement of dietary quality and the increase of human selenium levels may be the main reason for the relatively stable condition of Keshan disease in recent 10 years. The early diagnosis and treatment of chronic Keshan disease should be considered as the current clinical research focus of Keshan disease. The role of disease development is worth further exploration