目的探讨黔南地区布依族和苗族妇女围绝经期难治性高血压的影响因素,并比较两民族影响因素,为两民族妇女围绝经期难治性高血压的干预措施提供依据。方法对2013年3月-2016年2月在黔南布依族苗族自治州中医院就诊确诊为围绝经期难治性高血压女性患者325例作为研究对象。按民族分为布依族组167例,苗族组158例,采用自行设计的《黔南地区妇女围绝经期难治性高血压患病影响因素调查表》进行问卷调查,并对影响妇女围绝经期难治性高血压患病的相关因素进行Logistic多元回归分析。结果两民族妇女围绝经期难治性高血压患病影响因素比较:布依族组年龄和高血压病程年限分别与苗族组比较,差异均有统计学意义(t值分别为3.383、3.259,均P<0.01);布依族组甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)含量水平分别与苗族组比较,差异均有统计学意义(t值分别为5.538、2.423、3.334、3.532,均P<0.01);布依族组吸烟史、饮酒史、高血压家族史、血脂异常、糖耐量异常(IGT)、慢性肾脏病(CKD)、肥胖和糖尿病病例数分别与苗族组比较,差异均有统计学意义(χ2值分别为1.941、10.461、22.881、30.795、9.862、11.256、25.669、37.925,均P<0.01)。多因素Logistic回归分析结果表明,年龄(OR=5.352)、血脂异常(OR=4.687)、TG(OR=4.251)、TC(OR=4.113)、糖尿病(OR=4.028)、CKD(OR=3.908)和高血压病程(OR=3.822)是影响布依族妇女围绝经期难治性高血压因素。糖尿病(OR=4.025)、CKD(OR=3.917)和高血压病程(OR=3.764)是影响苗族围绝经期难治性高血压因素。结论黔南地区布依族和苗族妇女围绝经期难治性高血压患病影响因素有一定的差别。 Objective To explore the influencing factors of perimenopausal refractory hypertension in Buyi and Miao women in Qiannan area and to compare the influencing factors between the two ethnic groups to provide the basis for intervening measures of perimenopausal refractory hypertension in the two ethnic groups. Methods From March 2013 to February 2016, 325 female patients with perimenopausal refractory hypertension diagnosed in the Qiannan Buyi and Miao Autonomous Prefecture Chinese Medicine Hospital were selected as the research object. According to ethnic groups, 167 cases were divided into Buyi group and 158 cases in Miao group. A questionnaire survey was conducted by using self-designed Questionnaire on Influencing Factors of Refractory Hypertension in Perimenopausal Period in Qiannan Region. Logistic multiple regression analysis of the related factors of refractory hypertension. Results Comparison of influencing factors of peri-menopausal refractory hypertension in two ethnic women: The age and duration of hypertension in Buyi ethnic group were respectively compared with those in Miao group (t = 3.383, 3.259, P < <0.01). The levels of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) in Buyi group were significantly lower than those in Miao group (T = 5.538,2.423,3.334,3.532, all P <0.01); smoking history, drinking history, family history of hypertension, dyslipidemia, impaired glucose tolerance (IGT), chronic kidney The number of cases of CKD, obesity and diabetes mellitus were significantly different from that of the Miao group (χ2 = 1.941,10.461,22.881,30.795,9.862,11.256,25.669,37.925, all P <0.01). Multivariate Logistic regression analysis showed that age (OR = 5.352), dyslipidemia (OR = 4.687), TG (OR = 4.251), TC (OR = 4.113), diabetes And duration of hypertension (OR = 3.822) were the influencing factors of perimenopausal refractory hypertension in Buyi women. Diabetes mellitus (OR = 4.025), CKD (OR = 3.917), and duration of hypertension (OR = 3.764) were refractory hypertension factors affecting perimenopausal Miao people. Conclusion There are some influencing factors on the prevalence of refractory hypertension in Buyi and Miao women in Qiannan area.