目的分析甲型H1N1流感危重症的临床特点,总结治疗经验。方法回顾性分析20例甲型H1N1流感危重症的临床表现、实验室检查、影像表现。结果甲型H1N1流感危重症不仅见于婴幼儿和有原发基础病的儿童,也可见于体健的年长儿;常合并细菌、真菌、支原体、或其他病毒的感染;均伴有多脏器功能不全;好转后短期内随诊未留有后遗症。结论对甲型H1N1流感患儿早期作出正确的判断、及时积极的治疗有利于阻断和延缓病情进展、降低病死率、改善预后。 Objective To analyze the clinical features of Influenza A (H1N1) critically ill and to summarize the experience of treatment. Methods The clinical manifestations, laboratory tests and imaging findings of 20 cases of severe H1N1 influenza were retrospectively analyzed. Results Influenza A (H1N1) was not only found in infants and young children with primary underlying diseases, but also in elderly children with normal health. Infection with bacteria, fungi, mycoplasma or other viruses was often accompanied by multiple organs Dysfunction; improved after short-term follow-up did not leave sequelae. Conclusion Early diagnosis of Influenza A (H1N1) is correct in early stage. It is helpful to block and delay the progress of disease, reduce the mortality and improve the prognosis.