出生缺陷、胚胎停育、自然流产、死产、死胎以及畸胎都是造成不良孕产的因素。染色体异常是导致不良孕产史的常见原因之一。本研究对2005年1月至2014年11月来我院进行遗传咨询的不良孕产史患者的染色体核型进行了分析,现报道如下。1资料与方法1.1一般资料从2005年1月至2014年11月共有375对有不良孕产史夫妻来我院进行诊治,主要表现为自然流产、胚胎停育、死胎、畸胎、死产、出生缺 Birth defects, embryo shutdowns, spontaneous abortions, stillbirths, stillbirths, and teratosperms are all contributing factors to poor motherhood. Chromosomal abnormalities are one of the common causes of adverse pregnancy history. This study from January 2005 to November 2014 to our hospital for genetic counseling in patients with unhealthy history of maternal chromosome karyotype were reported, are reported below. 1 Materials and Methods 1.1 General Information From January 2005 to November 2014 a total of 375 couples with adverse pregnancy history to our hospital for diagnosis and treatment, mainly for spontaneous abortion, embryo suspension, stillbirth, teratogenicity, stillbirth, Lack of birth