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目的:观察中西医结合治疗慢性再生障碍性贫血(AA)的临床疗效。方法:选取68例慢性AA患者作为研究对象,采用随机数字表法分为观察组和对照组各34例,两组患者均采用常规西医治疗,观察组患者加用再障煎剂治疗,比较两组患者治疗60天后总有效率及治疗前、治疗60天后造血负调控因子指标水平。结果:经治疗,观察组患者治疗总有效率为88.24%,高于对照组的61.76%,差异具有统计学意义(P<0.05);与对照组比较,观察组患者治疗60天后TNF-α、IL-2水平明显降低,差异具有统计学意义(P<0.05)。结论:中西医结合治疗慢性再生障碍性贫血疗效明显,可降低造血负调控因子水平,值得临床推广应用。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of chronic aplastic anemia (AA). Methods: Sixty-eight patients with chronic AA were selected as study objects. Random number table was divided into observation group (34 cases) and control group (34 cases). Both groups were treated with conventional western medicine and observation group were treated with re-treatment decoction. Group 60 days after treatment, the total effective rate and before treatment, 60 days after treatment hematopoietic negative regulatory factor index level. Results: After treatment, the total effective rate of observation group was 88.24%, higher than that of control group (61.76%), the difference was statistically significant (P <0.05); Compared with control group, IL-2 levels were significantly lower, the difference was statistically significant (P <0.05). Conclusion: Integrative treatment of chronic aplastic anemia curative effect is obvious, can reduce the level of negative regulation of hematopoietic factors, worthy of clinical application.