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目的:探讨彩色多普勒超声在筛查胎儿先天性心脏病中的临床应用价值。方法:该院于2007年9月~2008年9月产前采用彩色多普勒超声筛查先天性心脏病胎儿,以探讨彩色多普勒超声诊断仪在胎儿先天性心脏病产前筛查中的临床意义。结果:共筛查1 116例孕妇,检出胎儿先天性心脏病10例,占0.90%;诊断胎儿先天性心脏病时平均孕周为(25.7±5.2)周(20~31周),其中4例检查在≤24周(40.00%)进行,6例(60.00%)检查在≤28周进行。本组10例检出的先天性心脏病胎儿中心内膜垫缺损2例,右室双出口1例,永存动脉干1例,单纯肺动脉狭窄1例,右室发育不良2例,心脏外翻畸形1例,单纯室间隔缺损2例。对10例检出异常者,8例终止妊娠,其中6例引产后尸检证实先天性心脏病存在;继续妊娠2例,患儿出生后经超声心动图确诊为先天性心脏病。结论:产前进行胎儿心脏彩色多普勒超声检查,能尽早明确诊断胎儿心脏异常,使大部分复杂心脏畸形在胎儿期就能得到及早诊断,这对减少新生儿生理缺陷有着重要的临床应用价值。
Objective: To explore the clinical value of color Doppler ultrasound in the screening of fetal congenital heart disease. Methods: The hospital from September 2007 to September 2008 prenatal color Doppler ultrasound screening of congenital heart disease fetus in order to explore the color Doppler ultrasound in prenatal screening of fetal congenital heart disease The clinical significance. Results: A total of 1 116 pregnant women were screened and 10 cases of fetal congenital heart disease were detected, accounting for 0.90%. The mean gestational age at diagnosis of fetal congenital heart disease was (25.7 ± 5.2) weeks (20-31 weeks), of which 4 Cases were performed at ≤24 weeks (40.00%) and six cases (60.00%) at ≤28 weeks. The group of 10 cases of congenital heart disease detected in fetal center of the intimal pad defects in 2 cases, 1 case of right ventricular double outlet, 1 case of permanent survival of the arteries, simple pulmonary stenosis in 1 case, 2 cases of right ventricular dysplasia, valgus deformity 1 case, simple ventricular septal defect in 2 cases. Of the 10 cases detected abnormalities, 8 cases of termination of pregnancy, of which 6 cases post-abortion confirmed by autopsy confirmed the existence of congenital heart disease; continue pregnancy in 2 cases, children born by echocardiography diagnosed as congenital heart disease. Conclusion: Prenatal fetal color Doppler ultrasonography can diagnose fetal heart abnormalities as soon as possible so that most complicated cardiac malformations can be diagnosed early in fetus, which has important clinical value in reducing neonatal physiological defects .