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目的研究不同类型格林巴利综合征(GBS)电生理特征,探讨神经电生理检测对GBS分型的价值。方法对54例GBS患儿进行前瞻性、动态的神经电生理检查,比较不同型GBS电生理特征。结果54例中有急性炎症性脱髓鞘型GBS26例(48%),轴索型GBS23例(43%),5例(9%)神经失电位不能分型。急性炎症性脱髓鞘型GBS电生理表现为:远端潜伏期延长(16例62%),神经传导阻滞(15例58%),神经传导速度降低(13例50%),F波潜伏期延长(5例19%),伴远端复合肌肉动作电位波幅降低(23例,89%),感觉神经电生理异常(11例,42%)。轴索型GBS电生理主要表现为运动神经远端复合肌肉动作电位波幅降低。结论不同型GBS电生理特征各异,神经电生理检测对GBS分型有重要诊断价值
Objective To study the electrophysiological characteristics of different types of GBS and explore the value of electrophysiological detection of GBS. Methods 54 cases of children with GBS were prospectively and dynamically electrophysiological examination, compared with different types of GBS electrophysiological characteristics. Results Among the 54 cases, 26 cases were acute inflammatory demyelinating GBS (48%), 23 cases (43%) were axial GBS, and 5 cases (9%) were unable to type. Acute inflammatory demyelination GBS electrophysiological manifestations: prolonged distal latency (62 cases of 62%), nerve block (15 cases of 58%), decreased nerve conduction velocity (13 cases of 50%), F-wave latency is prolonged (19% of 5 cases) with decreased amplitude of distal composite muscle action potential (23 cases, 89%) and sensory neurophysiological abnormalities (11 cases, 42%). Axolus GBS electrophysiology mainly for the motor nerve distal composite muscle action potential amplitude decreased. Conclusion Different types of GBS electrophysiological characteristics of different electrophysiological testing GBS classification has important diagnostic value