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目的进一步观察部分脾栓塞治疗肝硬化门静脉高压及脾功能亢进(简称脾亢)的应用价值。方法经下腔动脉插管对部分牌动脉用明胶海绵颗粒进行栓塞,观察其治疗作用。结果本文22例术后外周血白细胞和血小板计数均回升,其中19例恢复至正常水平,3例部分缓解,门静脉及脾静脉回缩,食道静脉曲张程度改善,凝血酶原时间(PF)缩短,凝血酶原活动度(PFA)增加,脑病发作次数减少,血氨水平下降,未出现严重并发症。结论部分脾栓塞是治疗肝硬化牌功能亢进、门静脉高压、缓解肝性脑病安全有效的治疗方法。
Objective To further observe the value of partial splenic embolization in the treatment of hepatic cirrhosis with portal hypertension and hypersplenism (referred to as hypersplenism). Methods Part of the inferior arteries were embolized with gelatin sponge particles through the cannulation of inferior vena cava to observe the therapeutic effect. Results In the 22 cases, peripheral blood leukocytes and platelet count increased in all cases, of which 19 recovered to normal level, 3 were partially relieved, the portal vein and splenic vein were retracted, the degree of esophageal varices was improved, the prothrombin time (PF) Prothrombin activity (PFA) increased, the number of encephalopathy episodes decreased, blood ammonia levels decreased, no serious complications. Conclusions Partial splenic embolization is a safe and effective treatment for hyperthyroidism with liver cirrhosis, portal hypertension and ehepatic encephalopathy.