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目的探讨纳洛酮联合醒脑静治疗急性乙醇中毒的临床疗效。方法选取2012年1月-2014年2月医院急诊科收治的98例急性乙醇中毒患者为研究对象。随机分为对照组和治疗组。除常规治疗外,对照组用0.9%氯化钠溶液20ml稀释盐酸纳洛酮0.4mg静脉注射,继以0.8~1.2mg纳洛酮加入0.9%氯化钠溶液250ml中静脉滴注;治疗组在对照组的基础上,用醒脑静20ml加入0.9%氯化钠溶液250ml溶液中静脉滴注,对比观察2组疗效。结果治疗组症状起效时间、症状减轻时间及症状消失时间明显优于对照组,总有效率大于对照组,差异均具有统计学意义(P<0.05)。结论醒脑静联合纳洛酮治疗急性乙醇中毒的临床疗效肯定,值得推广。
Objective To investigate the clinical efficacy of naloxone combined with xingnaojing in the treatment of acute alcoholism. Methods A total of 98 patients with acute alcoholism admitted from the hospital emergency department from January 2012 to February 2014 were enrolled in this study. Randomly divided into control group and treatment group. In addition to conventional treatment, the control group with 0.9% sodium chloride solution 20ml diluted naloxone 0.4mg intravenously, followed by 0.8 ~ 1.2mg naloxone added 0.9% sodium chloride solution 250ml intravenous infusion; treatment group in On the basis of the control group, intravenous drip was given to 20ml of Naoxintong 20ml in 250ml of 0.9% sodium chloride solution to compare the effects of the two groups. Results The symptom onset time, symptom relief time and symptom disappearance time in the treatment group were significantly better than those in the control group, and the total effective rate was higher than that in the control group. The differences were statistically significant (P <0.05). Conclusion Xingnaojing combined with naloxone in the treatment of acute ethanol poisoning clinical efficacy of certain, it is worth promoting.