论文部分内容阅读
目的:探讨单纯早发型重度子痫前期(SPE)患者与慢性高血压并发早发型SPE患者的期待治疗时间及妊娠结局的差异。方法:选取2011年6月1日~2014年2月30日于石家庄市第四医院产科诊治并分娩的单胎早发型SPE孕妇350例,其中慢性高血压并发早发型SPE患者60例(A)组,单纯早发型SPE患者290例(B组)。比较两组孕妇的期待治疗时间及母儿结局。结果:慢性高血压并发早发型SPE患者的最高收缩压和舒张压及胎儿生长受限发生率均明显高于单纯早发型SPE患者,期待治疗时间明显长于单纯早发型SPE患者,低蛋白血症及肺水肿发生率低于单纯早发型SPE患者,差异均有统计学意义(P<0.05)。两组孕妇的胎盘早剥、HELLP综合征和子痫等发生率、围产儿死亡率、新生儿死亡、胎死宫内、新生儿窒息的发生率比较,差异无统计学意义(P>0.05)。结论:慢性高血压并发早发型SPE患者较单纯早发型SPE的期待治疗时间长,在病情允许的情况下,通过严密监测母儿一般状况,可适当延长孕周,降低围产儿死亡率。
Objective: To investigate the differences between expectant treatment time and pregnancy outcome in patients with simple early-onset severe preeclampsia (SPE) and patients with chronic hypertension and early-onset SPE. Methods: A total of 350 pregnant women with singletonic early-onset type SPE diagnosed and delivered at the Fourth Hospital of Shijiazhuang City from June 1, 2011 to February 30, 2014 were enrolled in this study. Among them, 60 cases of chronic hypertensive patients with early onset SPE (60 cases) 290 patients with simple early-onset SPE (group B). The expectant treatment time and maternal and child outcomes of two groups of pregnant women were compared. Results: The highest systolic and diastolic blood pressure and fetal growth restriction rate in patients with chronic hypertension complicated with early-onset SPE were significantly higher than those in patients with early-onset SPE alone. The expected treatment time was significantly longer than those in patients with early-onset SPE, hypoproteinemia and The incidence of pulmonary edema was lower than that of patients with simple early-onset SPE, the differences were statistically significant (P <0.05). There was no significant difference in the incidence of placental abruption, HELLP syndrome and eclampsia, perinatal mortality, neonatal death, fetal death and neonatal asphyxia in both groups of pregnant women (P> 0.05). CONCLUSIONS: Patients with chronic hypertension complicated with early-onset SPE have longer treatment expectancy than those with early-onset SPE. Progression of gestational age can be prolonged and the perinatal mortality rate can be reduced by closely monitoring the general condition of the mother and child as the condition allows.