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1名62岁女性患者,因急性细菌性痢疾给予静脉滴注氟罗沙星葡萄糖注射液100ml(0.4g),1次/d。第3天患者出现周身肌肉、关节酸痛,体检:左侧膝关节、踝关节肿胀,腓肠肌内侧头外压痛阳性,关节活动时诱发疼痛。B超显示左膝关节积液,MRI示左膝关节前交叉韧带损伤、关节腔积液、关节周围软组织肿胀。实验室检查:血沉130mm/h、C反应蛋白42mg/L。立即停用氟罗沙星,给予关节制动、局部理疗,复查B超左侧膝关节恢复正常。3个月后,复查血沉、C反应蛋白均恢复正常。
A 62-year-old female patient was given 100 mL (0.4 g) of fleroxacin glucose injection intravenously once daily for acute bacillary dysentery. On the third day, patients showed whole body muscle and joint pain. Physical examination: left knee joint, ankle joint swelling, head-on tenderness of the head inside the gastrocnemius muscle, and joint pain. B ultrasound showed left knee joint effusion, MRI showed left anterior cruciate ligament injury, joint effusion, soft tissue swelling around the joint. Laboratory tests: ESR 130mm / h, C reactive protein 42mg / L. Immediate withdrawal of fleroxacin, given joint brakes, local physical therapy, review B-left knee back to normal. After 3 months, review ESR, C-reactive protein returned to normal.