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目的评估糖化清蛋白检测反映血糖水平的临床意义。方法采用糖化清蛋白(GA)快速检测法与糖化血红蛋白(HbA1c)检测法分别检测糖尿病与非糖尿患者血糖水平,分析二者的相关性以及糖化清蛋白快速检测法的精确性与灵敏度。结果糖化清蛋白快速检测法精密度良好,且抗干扰能力较好,均符合临床检测的要求。GA与HbA1c、空腹血糖(FPG)、餐后2h血糖(2hBG)均呈良好的正相关性,其回归方程分别为Y=0.89X+0.21,Y=0.84X+0.11,Y=0.92X+0.15;r值分别为0.94、0.92、0.96(P<0.01)。结论 GA快速检测法可反映糖尿病患者近期整体血糖水平,具有重要临床价值。
Objective To evaluate the clinical significance of detecting glycated albumin to reflect blood sugar level. Methods The rapid test of glycosylated albumin (GA) and the test of glycosylated hemoglobin (HbA1c) were used to detect the blood glucose level of diabetic and non-diabetic patients respectively. The correlation between the two and the accuracy and sensitivity of the rapid test for glycated albumin were analyzed. Results Saccharification albumin rapid detection of good precision, and better anti-interference ability, are in line with clinical testing requirements. GA had a positive correlation with HbA1c, fasting plasma glucose (FPG) and postprandial 2h blood glucose (2hBG). The regression equation was Y = 0.89X + 0.21, Y = 0.84X + 0.11, Y = 0.92X + 0.15 ; r values were 0.94,0.92,0.96 (P <0.01). Conclusion GA rapid test can reflect the recent overall blood glucose levels in patients with diabetes, has important clinical value.