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[目的]分析重庆市2009年1~11月甲型H1N1流感的流行特征,预测发病趋势,为制定防控策略提供科学依据。[方法]对重庆市甲型H1N1流感病例进行描述性流行病学分析,监测哨点医院门诊流感样病例就诊比,监测哨点医院流感样病例、急性呼吸道感染病例的流感病毒谱和优势毒株,抽样调查重庆市人群甲型H1N1流感血清抗体水平,预测发病趋势。[结果]2009年6月13日,重庆市确认首例甲型H1N1流感疫情,截止2009年11月30日,累计报告甲型H1N1流感病例2179例,无死亡,发病率为7.74/10万。甲型H1N1流感在重庆的流行过程经历了输入个案病例、输入聚集性病例、病例本土化并出现多点聚集3个阶段,流行高峰为10月。病例分布于全市40个区县,主城区发病率高于远效县。男︰女=1.4︰1,报告发病以10~20岁组最多,职业以学生为主。400名人群甲型H1N1流感病毒血清抗体监测结果,阳性率为15.40%。[结论]2009年重庆市发生了流感流行,甲型H1N1流感已由输入转为本土,是导致流感流行的优势毒株。2009年重庆市流感的流行特征与往年不同;重庆市将继续出现甲型H1N1流感流行;发病者的年龄、职业、地域范围将更加广泛;症状很轻或无明显临床症状的感染者是引起疫情扩散蔓延的重要危险因素之一。
[Objective] To analyze the epidemic characteristics of Influenza A (H1N1) in Chongqing from January to November in 2009 and predict the trend of the disease, so as to provide a scientific basis for making prevention and control strategies. [Methods] Descriptive epidemiological analysis of Influenza A (H1N1) cases in Chongqing was carried out to monitor the outpatient flu-like cases in sentinel hospitals, the flu-like cases in sentinel hospitals, the influenza virus spectrum in acute respiratory infections and the dominant strains , Sample survey of Chongqing population influenza A (H1N1) serum antibody levels, predict the trend. [Results] On June 13, 2009, the first confirmed case of Influenza A (H1N1) in Chongqing was confirmed. As of November 30, 2009, a total of 2179 cases of Influenza A (H1N1) were reported, with a death rate of 7.74 / 100 000. Influenza A H1N1 flu in Chongqing experienced the process of entering a case of input cases, enter clustering cases, localized cases and multi-point aggregation of three stages, the peak of the epidemic in October. Cases distributed in the city’s 40 districts and counties, the main urban area incidence is higher than Yuanxian County. Male: female = 1.4: 1, report the incidence of 10 to 20-year-old group up to occupation-based students. The results of surveillance of serum antibody of Influenza A (H1N1) virus from 400 people showed that the positive rate was 15.40%. [Conclusion] Influenza pandemic occurred in Chongqing in 2009, Influenza A (H1N1) flu was transformed from the imported to the local one, which was the predominant strain that caused the flu epidemic. The epidemic characteristics of influenza in Chongqing in 2009 are different from those in previous years; Chongqing will continue the pandemic of influenza A (H1N1); the age, occupation and geographical scope of the patients will be more extensive; those with mild symptoms or no obvious clinical symptoms are the cause of epidemic One of the important risk factors for spreading and spreading.