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目的:通过对门诊退药问题的帕累托图分析,查找主要因素,减少退药现象的发生。方法:应用excel软件统计分析2010年4月～2011年6月退药记录,同时按退药原因、退药品种分别进行帕累托图分析。结果:在10种退药原因中,4种原因构成主要因素,在13类药物中4类药物构成主要因素。结论:针对造成退药问题的主要因素,加强ADR(药品不良反应)/ADE(药品不良事件)的管理至关重要,特别是抗菌药、中成药、消化系统用药、心血管系统用药的ADR/ADE监测,开展临床药学工作,加强医生与患者的沟通,完善退药制度,采取有效干预措施,减少退药造成的药品质量隐患,保证患者用药安全。
OBJECTIVE: To find out the main factors through the Pareto chart analysis of out-patient drug withdrawal and to reduce the occurrence of drug withdrawal. Methods: The data of withdrawal from April 2010 to June 2011 were statistically analyzed by Excel software. Pareto chart analysis was conducted according to the reasons for withdrawal and the withdrawal varieties. Results: Of the 10 reasons for withdrawal, 4 causes constitute the main factor, and among the 13 categories, 4 types of drugs constitute the main factor. CONCLUSIONS: In order to strengthen the management of ADR / ADE, the main factors causing the withdrawal of drugs are particularly important. Antibiotic drugs, proprietary Chinese medicines, digestive system drugs and cardiovascular system drugs are important for the management of ADR / ADE monitoring, to carry out clinical pharmacy work, to strengthen communication between doctors and patients, improve the withdrawal system, to take effective interventions to reduce drug quality problems caused by the withdrawal of drugs to ensure the safety of patients medication.