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目的:探讨小剂量布托啡诺复合丙泊酚在老年患者无痛肠镜检查中的应用价值。方法:将120例ASAⅠ~Ⅱ级拟行无痛肠镜检查的老年患者随机分成3组,每组40例,P组采用丙泊酚麻醉,B组采用布托啡诺复合丙泊酚麻醉,F组采用芬太尼复合丙泊酚麻醉。观察3组患者麻醉前、麻醉后及意识恢复后收缩压(SBP)、心率(HR)、呼吸(R)和血氧饱和度(SpO2)等指标。记录操作时间和清醒时间、丙泊酚用量。比较3组麻醉效果。结果:P组患者清醒时间、丙泊酚用量、静脉刺激痛均明显高于B、F两组(P<0.05)。B组呼吸抑制发生率明显小于P、F两组(P<0.05)。3组患者麻醉效果差异无统计学意义(P>0.05)。结论:布托啡诺用于老年患者无痛肠镜检查麻醉效果好,可减少丙泊酚用量,并发症少。
Objective: To investigate the value of low dose butorphanol combined with propofol in painless colonoscopy in elderly patients. Methods: A total of 120 ASA Ⅰ ~ Ⅱ elderly patients undergoing painless colonoscopy were randomly divided into 3 groups, 40 cases in each group. Group P was anesthetized with propofol, group B was treated with butorphanol combined with propofol, Group F was treated with fentanyl and propofol. The systolic blood pressure (SBP), heart rate (HR), respiration (R) and oxygen saturation (SpO2) were observed before anesthesia, after anesthesia and consciousness recovery in 3 groups of patients. Record the operation time and awake time, the dosage of propofol. Compare 3 groups of anesthesia effect. Results: The awake time, the dosage of propofol and the pain of venous irritation in group P were significantly higher than those in groups B and F (P <0.05). The incidence of respiratory depression in group B was significantly lower than that in groups P and F (P <0.05). There was no significant difference in anesthesia between the three groups (P> 0.05). Conclusion: Butorphanol is a good analgesic for painless colonoscopy in senile patients. It can reduce the dosage of propofol and has fewer complications.