论文部分内容阅读
目的:探讨壳聚糖对“网脱Ⅰ号”口服液的絮凝除杂效果。方法:壳聚糖用于“网脱Ⅰ号”口服液的絮凝除杂,以澄明度、有效成分含量为指标,对壳聚糖的用量、药液浓缩比进行优选,并与醇沉工艺进行比较。结果:壳聚糖絮凝法与醇沉法同样能使药液澄清,在有效成分的保留上,前者优于后者。结论:壳聚糖絮凝法可用于“网脱Ⅰ号”口服液的絮凝除杂工艺。
Objective: To investigate the effect of chitosan on the flocculation and impurity removal of “net off Ⅰ ” oral solution. Methods: Chitosan was used in the flocculation and impurity removal of “net off Ⅰ ” oral solution, the content of chitosan and the concentration of chitosan were selected as the indexes of clarity and effective ingredient concentration, Process comparison. Results: Chitosan flocculation and alcohol precipitation method can clarify the same liquid, the retention of the active ingredient, the former is better than the latter. Conclusion: The flocculation method of chitosan can be used in flocculation and impurity removal process of “net off Ⅰ ” oral solution.