弥散性血管内凝血(disseminated intravascularcoagulation,DIC),是一种以血液凝血-抗凝血与纤溶-抗纤溶失衡为病理特征的临床-出血综合征[1-2]。DIC是新生儿危重急症之一,约占ICU住院患儿的7.8%[3],具有起病急,发展迅速的特点,它不是一个独立的疾病,而是由多种致病因素引起的 Disseminated intravascular coagulation (DIC) is a clinically-haemorrhagic syndrome with pathological features of blood coagulation-anticoagulation and fibrinolytic-antifibrinolytic imbalances [1-2]. DIC is one of the critically ill neonates, accounting for about 7.8% of hospitalized children with ICU [3]. It has the characteristics of acute onset and rapid development. It is not an independent disease but caused by a variety of pathogenic factors