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目的 :筛选银黄酮片的最佳处方。方法 :考察糊精、羧甲基淀粉钠、微晶纤维素和低取代羟丙基纤维素对银黄酮片的质量影响。结果 :筛选的最佳处方为5 %低取代羟丙基纤维素。按照最佳处方制备的银黄酮片崩解度大为提高。结论 :本法处方合理 ,工艺简单 ,所制备的银黄酮片适合临床应用。
Objective: To screen the best prescription of silver flake tablets. Methods: The effects of dextrin, sodium starch glycolate, microcrystalline cellulose and low-substituted hydroxypropyl cellulose on the quality of silver flavanone tablets were investigated. Results: The best prescription for screening was 5% low-substituted hydroxypropylcellulose. Silver flavanone tablets prepared in accordance with the best prescription greatly improve the degree of disintegration. Conclusion: The prescription is reasonable and the process is simple. The prepared silver flavonoids tablets are suitable for clinical application.