妊娠高血压综合征(下称妊高征)是一种可引起孕产妇及围产儿死亡的严重产科并发症,其发病机制尚不清楚。临床病理学研究显示,妊高征发生时有血管内皮细胞损伤的形态学改变。进一步的研究证明,血管内皮受损时产生的一系列物质在妊高征临床表现出现之前已在血浆中明显升高,从而证 Pregnancy-induced hypertension (PIH) is a serious obstetric complication that can cause maternal and perinatal deaths, and its pathogenesis is unclear. Clinicopathological studies have shown that there is a morphological change of vascular endothelial cell injury when PIH occurs. Further studies have shown that a series of substances produced during vascular endothelial damage have been significantly increased in plasma before the clinical manifestations of PIH appear,