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目的了解广西壮族自治区感染性腹泻实际发病情况及疾病负担。方法采用整群随机抽样的方法进行抽样,对抽中的社区或村屯的所有居民共2万余人分别于2007年8月和12月进行2次入户调查,数据录入并进行发病率、伤残调整损失寿命年(DALYs)和经济负担等指标的计算。结果两周发病率和病死率分别为1.04%和0.00%,夏季两周发病率(1.21%)高于冬季(0.89%)(χ2=10.0578,P=0.0015)。推算的全人群年发病率为0.2887次/人年,以<5岁年龄组为高,其中0岁~组为1.4428次/人年;男、女性分别为0.3091次/人年和0.2673次/人年。腹泻病人就诊率28.05%、住院率2.04%,自己买药、使用家庭药箱治疗和不作任何治疗者分别占37.10%,13.80%和21.04%。总DALYs为0.1935/千人年,以中青年为高,其中20~49岁为0.2971/千人年。所导致的直接经济损失和间接经济损失人均分别为43.02和18.35元,总经济损失人均61.37元,推算出广西因腹泻导致的年经济损失为87896.61万元。结论广西腹泻病以<5岁儿童为高危人群,患病后不就诊现象相当普遍,依然导致一定的疾病负担。
Objective To understand the actual incidence of infectious diarrhea and the burden of disease in Guangxi Zhuang Autonomous Region. Methods The method of cluster random sampling was used for sampling. A total of more than 20,000 people from all the communities in the community or village were surveyed in August and December 2007 respectively. The data were collected and morbidity was recorded. Disability-adjusted life expectancy years (DALYs) and economic burden and other indicators of calculation. Results The two-week morbidity and mortality were 1.04% and 0.00% respectively. The two-week incidence in summer (1.21%) was higher than that in winter (0.89%) (χ2 = 10.0578, P = 0.0015). The estimated annual incidence rate of the whole population was 0.2887 / person year, which was higher in <5 years old group, of which 1.4428 times / person year in 0 years old group; 0.3091 times / person year and 0.2673 times / person in male and female respectively year. Diarrhea patients visiting rate 28.05%, hospitalization rate 2.04%, buy their own medicine, the use of family medicine cabinet treatment and without any treatment accounted for 37.10%, 13.80% and 21.04%. The total DALYs was 0.1935 per thousand person-years, of which middle-aged and young people were the highest, of which, 0.2971 per thousand-year-olds were 20-49 years old. The direct economic losses and indirect economic losses were 43.02 yuan and 18.35 yuan respectively, and the total economic losses were 61.37 yuan per capita. It is estimated that the annual economic loss due to diarrhea in Guangxi is 878.9661 million yuan. Conclusions Guangxi diarrheal disease is a high-risk group of children <5 years of age. The prevalence of non-treatment after the illness is quite common, still leading to certain disease burden.