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目的观察芬太尼持续静脉输注用于小儿术后镇痛的效果及不良反应。方法ASAⅠ-Ⅱ级择期手术患儿115例,术后持续静脉输注芬太尼20ug·kg-1+昂丹司琼4mg-8mg,术后4,24,50小时观察记录,采用镇痛和镇静共同评估,观察不良反应的发生。结果本组无痛99例,轻度疼痛10例,中度疼痛5例,无效1例。镇静效果:轻度镇静90例,中度镇静25例,恶心呕吐发生15例,无呼吸抑制,尿潴留,皮肤瘙痒等发生。结论芬太尼持续静脉输注用于小儿术后镇痛是有效安全的。
Objective To observe the effects and adverse reactions of continuous intravenous infusion of fentanyl for pediatric postoperative analgesia. Methods A total of 115 ASAⅠ-Ⅱ patients undergoing elective surgery underwent continuous intravenous infusion of 20ug · kg-1 fentanyl and 4mg-8mg ondansetron. Postoperative analgesia was recorded at 4, 24 and 50 hours after operation. Sedation jointly assessed to observe the occurrence of adverse reactions. Results 99 cases of painless in this group, mild pain in 10 cases, 5 cases of moderate pain, 1 case of ineffective. Sedative effect: mild sedation in 90 cases, moderate sedation in 25 cases, nausea and vomiting occurred in 15 cases, no respiratory depression, urinary retention, skin itching and so on. Conclusions Continuous intravenous infusion of fentanyl is effective and safe for postoperative analgesia in children.