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目的探讨注射泵与传统注射器推注阿托品用于有机磷农药中毒的临床治疗效果。方法将100例有机磷农药中毒的患者随机平均分成两组,每组50例,在前序相同处理下,注射泵组以阿托品50mg每小时泵入,达到阿托品化后逐渐减量维持1周,传统注射器推注组以阿托品10mg每20分钟肌注1次,直至达到阿托品化后逐渐减量维持1周。临床观察分析两组患者使用阿托品后达到阿托品化的时间及使用阿托品的总剂量。结果注射泵组达到阿托品化的时间为3.12±1.00小时,而推注组为5.60±1.60小时;注射泵组阿托品使用总剂量为6.10±1.50g,而推注组为11.60±2.50g。结论注射泵组达到阿托品化的时间明显短于传统静脉推注组的时间(P<0.05),注射泵组的阿托品使用总剂量明显少于传统静脉推注组的使用总量(P<0.05),注射泵用于有机磷农药的阿托品治疗优于传统注射器推注的阿托品的治疗。
Objective To investigate the clinical effect of syringe pump and traditional syringe bolus atropine on organophosphorus pesticide poisoning. Methods 100 cases of organophosphorus pesticide poisoning were randomly divided into two groups of 50 patients in each group under the same pre-treatment, the injection pump group to pump 50mg atropine per hour, to achieve atropine and gradually reduced to maintain a week, The conventional syringe bolus group was intramuscularly injected with atropine 10 mg once every 20 minutes until the dose of atropine was gradually reduced and maintained for 1 week. Clinical observation Analysis of two groups of patients using atropine to achieve atropine time and the total dose of atropine. Results The duration of atropine infusion in the injection pump group was 3.12 ± 1.00 hours compared with 5.60 ± 1.60 hours in the bolus injection group. The total dose of atropine in the injection pump group was 6.10 ± 1.50g compared with 11.60 ± 2.50g in the bolus group. Conclusion The duration of atropineization in the injection pump group was significantly shorter than that in the traditional intravenous bolus group (P <0.05). The total dose of atropine in the injection pump group was significantly less than that of the traditional intravenous bolus group (P <0.05) , Syringe pumps for the treatment of atropine organophosphate pesticides than traditional syringe bolus atropine treatment.