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患者男,66岁。无明显诱因出现发热,咳嗽、咳痰,头晕、乏力20余天,于当地医院就诊,症状好转,白细胞总数计数一直下降。次月转至我院进一步就诊。体检:贫血貌,皮肤无出血点及瘀斑。入院血常规示:WBC 6.9×10~9/L,RBC3.21×10~(12)/L,Hb 86g/L,PLT 56×10~9/L。分类:幼稚细胞66%,骨髓免疫分型示急性早幼粒细胞白血病。骨髓染色体示:2个中期相细胞可见1号和3号染色体易位,2号和另一条3号染色体易位,并怀疑存在15号和17号染色体易位;
Patient male, 66 years old. No obvious incentive to fever, cough, sputum, dizziness, fatigue more than 20 days, at a local hospital for treatment, symptoms improved, the total white blood cell count has been declining. The next month to our hospital for further treatment. Physical examination: anemia appearance, no bleeding spots and ecchymosis Admission blood showed: WBC 6.9 × 10 ~ 9 / L, RBC3.21 × 10 ~ (12) / L, Hb 86g / L, PLT 56 × 10 ~ 9 / L. Category: immature cells 66%, bone marrow immunophenotype acute promyelocytic leukemia. Bone marrow staining showed that two metaphase cells showed translocations of chromosomes 1 and 3, translocations of chromosome 2 and 3, and suspicion of chromosomal translocations 15 and 17;